http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-199161-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f4246e8fcebf17c365aced017a04c61 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 |
filingDate | 1991-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1993-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c74329d5d2f54dd4ea0f58465617bfb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f25d7b65dbbdc2eccfdd3c4de1e61242 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d0b5bc5aef49974b193884775cdc828 |
publicationDate | 1993-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-199161-B |
titleOfInvention | Improvements process for chemical reactions on camptothecin or analogs thereof |
abstract | A process for preparing a reduced camptothecin derivative in which a camptothecin substrate bearing a reducible substituent is hydrolyzed under alkaline conditions to open the lactone E ring and form a carboxylate salt. The carboxylate salt is reduced to form a reduced carboxylate salt which is then contacted with acid to reform the lactone E ring. This procedure results in substantially increased yields of camptothecin derivatives. |
priorityDate | 1990-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.