| abstract |
The present invention is in the fields of pharmaceuticals, formulations chemistry and pharmacology. The invention generally relates to azelastine or its pharmaceutically acceptable salts or esters thereof, including azelastine hydrochloride as defined by the claims. In some embodiments, the invention provides pharmaceutical compositions containing azelastine hydrochloride formulated for use as nasal sprays and / or ocular solutions or drops, as well as dosage formulations for oral and pulmonary administration. The invention also relates to methods of using such compositions in treating, ameliorating or preventing symptoms associated with various allergic and non-allergic conditions. |