| abstract |
Hydrogen atom (s) of the hydroxyl hydroxyl group (s) at the 2-position and / or 4-position of the alkyl alkyl aldehyde region; C1-15alkyl, C1-15alkenyl ,, CH2COOH, CH2COO (C1-15) alkyl, C (= O) (C1-15) alkyl, C (= O) (CH2) 1-15COOH, nicotininoyl or isonicotinoyl etc. ligands belonging to nuclear receptor PPARs (peroxisome proliferator activated receptors) as compounds selected from the group consisting of homologs of ascofuranone and ascofuranone with at least one substitution of at least one oryl aldehyde region. These ligands are; diabetes; hypertension or cerebrovascular diseases; arteriosclerosis; diabetes complications; chronic inflammation; cachexia; cancers of the digestive system, etc. It is beneficial for its treatment and / or prevention. |