| abstract |
The present invention relates to compounds with the following formula: in this compound, in particular, the symbols R1, R2 and R3 are each independently hydrogen; a halogen atom; a (C1-C5) alkyl; a (C1-C5) alkoxy; a trifluoromethyl or an S-R group in which the R symbol is a (C1-C5) alkyl; R4 and R5 are a (C1-C5) alkyl; An alkynyl having 3 to 5 carbon atoms; a (C3-C5) cycloalkyl or a Ra-X- (C1-C2) alkyl group having the symbol Ra (C1-C3) alkyl and the symbol X; R6 is -CHR7R8, whereas R7 is a phenyl group which can be substituted at the 3-, 4- and 5-positions with one or more Z 'radicals that are halogen; a (C1-C5) alkyl; A (C1-C5) alkyl-X- or (C1-C3) alkyl-X- (C1-C2) alkyl having the X symbol O; a methylenedioxy group; and the symbol R8 is a (C1-C6) alkyl; a (C3-C5) cycloalkyl (C1-C3) alkyl; or a (C1-C3) alkyl-X- (C1-C3) alkyl where the X symbol is O. These compounds exhibit affinity for CRF receptors. |