| abstract |
The present invention relates to the use of adrenaline, or an addition salt thereof, as a key process of an industrial-size asymmetric hydriding process and a special sequence of subsequent processing steps, in which the [Rh (COD) Cl] 2 as a catalyst and a spiral, For example, two decade phosphinligands (2R, 4R) -4- (dicyclohexylphosphino) -2- (diphenylphosphino-methyl) -N-methyl-amino-carbonyl-pyrrolidine are used as the catalyst system. |