http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TR-200103472-T2

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filingDate 2000-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_038818efe6295ac50df7b6b735b87843
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publicationDate 2002-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TR-200103472-T2
titleOfInvention Crystalline (2-benzhydryl-1-azabicyclo [2.2.2] oct-3-yl) - (5-iso-propyl-2-methoxybenzyl) -amine citrate polymorphs as NK-1 receptor antagonists.
abstract The two crystalline polymorphic forms of (2-Benzhydryl-1-azo-bicyclo [2.2.2] oct-3-yl) - (5-isopropyl-2-methoxy benzyl) -amine citrate monohydratin (monohydrates) are Form A p and Form B . A pharmaceutical composition containing at least one of these polymorphs has advantageous stability for the formulation intended to treat acute breastfeeding in a patient receiving chemotherapy. Administration of this pharmaceutical composition is conventionally oral and intravenous, preferably by tablet or capsule. The method of preparing A and B Forms is also explained.
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