abstract |
Dehydroepiandrosterone dehydroepiandrosterone sulfate, an amount of a sex steroid precursor selected from the group consisting of androst-5-en-3beta, 17beta-diol and compounds converted in vivo to one, and selective estrogen receptor modulator, in particular, the structure of the general structure (1). new methods for the medical treatment and / or inhibition of their development in arteriosclerosis, hyperlipidemia, hypercholesterolemia, breast cancer or osteoporosis in sensitive warm-blooded animals, including humans. Additional administration of bisphosphonates in combination with selective estrogen receptor modulators and / or a sex steroid precursor; It is reported for the medical treatment of osteoporosis and / or inhibition of its development. Pharmaceutical compositions for delivery of active ingredient and kits useful to the invention are also reported. |