| abstract |
Invention, R1 is hydrogen, lower alkyl or hydroxy-lower alkyl; R2 is furyl, thienyl, pyridyl or phenyl optionally substituted by 1 to 3 substituents selected from lower alkyl, lower alkoxy, halogen, cyano, CF3 or-N (R4) 2; R3 can optionally from lower alkyl, lower alkoxy, halogen, acetyl, cyano, hydroxy-lower alkyl, -CH2-morpholin-4-yl, lower alkyl-oxy-lower alkyl, lower alkyl-N (R4) 2 or CF3. naphthyl or phenyl substituted with 1 to 3 selected substituents; R4 independently of one another (RS) -2-phenyl-1- (toluene-4-sulfonyl) -pyrrolidine and (RS) -1- (toluene-4-sulfonyl) -2-p-tolyl-pyrrolidine hydrogen or compounds of the general formula (I) where it is lower alkyl, as well as their pharmaceutically acceptable salts (FORMUL VAR). |