| abstract |
The present invention relates to new pharmaceutical uses of compounds that act as nitric oxide synthase (NOS) inhibitors. Specifically, this is a single or other active agent in the treatment of NOS inhibitors, particularly selective neuronal NOS (N-NOS) inhibitors: (a) in combination with the substance; (b) in combination with an anti-inflammatory agent in the treatment of inflammatory disorders; (c) in combination with a narcotic analgesic (eg, opiates such as morphine or demerol) in the treatment of pain; (d) alone or in combination with other active ingredients for the development of perception; and (e) its use alone or in combination with other active ingredients in the treatment of sleep disorders such as apnea, narcolepsy and insomnia. |