| abstract |
R is an organic residue whose molecular weight does not exceed 400 and is bound to the neighboring sulfur atom via carbon and contains carbon, hydrogen and optionally oxygen, sulfur, nitrogen and / or halogen atoms; R1 is hydrogen, lower-alkyl or phenyl; and A is a secondary, tertiary or quaternary nitrogen atom, which is attached directly to the propenyl group and whose molecular weight does not exceed 400 and is substituted with a residue containing carbon, hydrogen, and optionally oxygen, sulfur, nitrogen and / or halogen atoms ( Sephalosporin derivatives of I) as well as their easily hydrolyzable esters, pharmaceutically acceptable salts of these compounds, and hydrates of the compounds of formula (I) and their esters and salts are provided. |