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filingDate 1999-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c238623236da9d8da0c24d8b71c95f63
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publicationDate 2001-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TR-200003135-T2
titleOfInvention Preparation of B-lactam antibiotics in the presence of urea or amidine.
abstract This invention provides an improved process for the preparation of B-lactam antibiotic compounds in the presence of urea or derivatives thereof and / or amide or derivatives thereof. B-lactam compounds, (a) D-phenyl-glycine, Dp-hydroxyphenyl-glycine, D-2 (1,4-cislohexadien-1-yl) glycine or (2-aminothiazol-4- in one or more organic solutions yl) - (2-methoxy-imino-acetic acid) containing 6-amino-penicillenic acid, 7-amino-cephalosporanic acid, 7-amino-3'-desacetoxysphalosporanic acid or 3-chloro- The acylation reaction of 7-aminodesacetoxidesmethylcephalosporanic acid or derivatives thereof (b) is a urea or derivative to B-lactam solution or suspension obtained by melting or forming a suspension of a crude B-lactam compound in a solution containing water and / or one or more organic solvents, and / or a B-lactam compound defined by the addition of amides or derivatives into an acidic solution (CONTINUED)
priorityDate 1998-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 28.