| abstract |
This invention relates to methods for the treatment of insulin resistance in a mammal, and an effective amount of a combination of formula (I), the variables of which are described in the specification, or diastereomerically enriched, enantiomerically enriched, enasteriomerically enriched or enantiomerically enriched. It consists of applying isomers or pharmaceutically acceptable salts and their drug precursors to said mammal. Compounds of formula (1) are growth hormone secretagogues and are therefore useful for increasing the level of growth hormone in the living thing. In another aspect, the invention provides certain intermediates and certain intermediates which are useful in the synthesis of the above compounds and certain processes useful for the synthesis of the compounds of formula (I). |