abstract |
Treatment of arthritis, cancer, synergy with cytotoxic anticancer agents, tissue ulceration, macular degeneration (mottling), restenosis (re-narrowing of an enlarged canal), periodontal diseases, epidemolysis bullosa, a condition selected from a group selected from scleritis (sclera inflammation). R1, R2, R3, R4, R5, R6, which are useful in the treatment of other diseases, in combination with standard NSAIDs and analgesics and are characterized by matrix metalloproteinase activity, including AIDS, sepsis, septic shock and TNF production. A compound of formula (I) wherein Ar is as described above. |