| abstract |
Benzoylguanidines according to Formula I, which have the meanings given in the formulas R (1) to R (4), are valuable antiarrhythmic drug substances with cardioprotective components, and also prevent the occurrence of damages in the formation of ischemic-induced damages, especially ischemic-induced cardiac arrhythmias. . These drug substances can be used in the treatment of acute or chronic injuries caused by ischemic origin as a result of preventing the cellulose Na + / H + - change mechanism. In addition, these drugs have a strong preventive effect on the profiling of cells. The drug substance is suitable for use to prevent the formation of high blood pressure. |