http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TN-SN98063-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-22 |
| filingDate | 1998-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d3a7a0000527316e1a5cf1741ffc962 |
| publicationDate | 2005-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TN-SN98063-A1 |
| titleOfInvention | METHOD OF MANUFACTURING SERTINDOLE |
| abstract | A PROCESS FOR THE MANUFACTURE OF SERTINDOLE COMPRISING THE PREPARATION OF GLYCINE N- (4 -FLUOROPHENYL) - N - (2- CARBOXY - 4 CHLOROPHENYL, BY REACTING A METAL ALKALINE ACID 2.5 - DICHLOROBENZOIC NICOLINE - (4- FLUOROPHEYLE) IN AN AQUEOUS ALKALINE MEDIUM IN THE PRESENCE OF COPPER AS A CATALYST; CYCLISATION OF GLYCINE N- (4 - FLUOROPHENYL) - N - (2 - CARBOXY - 4 CHLOROPHENYLE) WITH 3- ACETOXY -INDOLE CORRESPONDING; - ACETOXY - INDOLE AND SUCCESSIVE ELIMINATION OF H2O BY OBTAINING SO 5 - CHLORO - 1 (4 -FLUOROPHENYL) INDOLE AND REACTION OF THIS COMPOUND WITH 1 - (2 - CHLOROETHYLE) - 2 - IMIDAZOLIDINONE IN THE PURPOSE OF OBTAINING THE SERTIN ALTERNATIVELY, THE 5 - CHLORO - 1 (4 FLUOROPHENYLE) 3- (1, 2, 3, 6 TETRAHYDROPYRIDIN -4YL) INDOLE IS FIRST REACTION WITH THE & - (2- CHLOROPHENYLE) - 2- IMIDAZOLIDINONE THEN SUBIT REDUCTION BY OBTAINING SERTINDOLE, THIS PROCESS USES SUITABLE REAGENTS AND SOLVENTS AND AUTHORIZED IN LARGE-SCALE MANUFACTURE. ELSEWHERE, GOOD TOTAL RETURNS ARE OBTAINED. |
| priorityDate | 1997-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.