| abstract |
1.5 BENZODIAZEPINE COMPOUNDS HAVING THE FOLLOWING FORMULA (I): IN WHICH R1 IS CHOSEN BETWEEN C1-C6 ALKYL, C3-C6 CYCLOALKYL, PHENYL OR PHENYL SUBSTITUTED. R2 IS SELECTED BETWEEN C3-C6 ALKYL, C3-C6 ALKENYL, BENZYL, PHENYL C1-C3 ALKYL OR PHENYL SUBSTITUTED OR: NR1R2 FORMALLY SET OF 1, 2,3,4-TETRAHYDROQUINOLINE OR BENZAZEPINE, MONO, DI OR TRISUBSTIT BY C1-6 ALKYLE, C1-6 ALKOXY OR SUBSTITUTE HALOGEN; P IS A WHOLE NUMBER 0 OR 1; Q IS A WHOLE NUMBER 0 OR 1; R IS A WHOLE NUMBER 0 OR 1; T IS A WHOLE NUMBER 0 OR 1 HAS CONTION THAT IF R IS 0, T IS ALSO 0; R3, R5 AND R6 ARE INDEPENDENT OF HYDROGEN OR C1-6 ALKYL; R4 IS C1-6 QLKYLE OR C1-6 ALKENYLE. R7 IS CHOSEN FROM A GROUP CONSISTING OF HYDROGEN, C1-6 ALKYLE, C1-6 CYCLOALKYLE, C1-6 ALKENYL, PHENYLE, PHENYLE SUBSTITUE, NAPHTHY, HETEROARYL, HETEROARYL SUBSTITUE, BICYCLOHETEROARYETHYLEROHETEROARYBUHETEROARY OR FORMALLY TOGETHER A RING SATURATED AT 5,6 OR 7 BRANCHES POTENTIALLY INTERRUPTED BY 1,2,33 or 4 HETEROATOMES OF N, S OR O WITH THE RESERVE THAT IN NO GROUP OF TWO HETEROATOMES OF O OR S, THESE ATOMS ARE NOT RELATED TOGETHER. M IS A WHOLE NUMBER CHOSEN BETWEEN 0,1,2,3 or 4; R8 AND R9 ARE CHOSEN AMONG A RANGE OF SUBSTITUTES. Z IS HYDROGEN OR HALOGEN. NEW INTERMEDIATES, A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF OBESITY, BILARIAN VESICLE STASE, PANCREATIC SECRETION DISORDERS, METHODS OF TREATMENT OF THIS TYPE AND PROCESSES FOR THE PREPARATION OF THE FOLLOWING COMPOUNDS (I). |