| abstract |
the present invention relates to a nucleic acid, preferably to ghrelin binding, this nucleic acid comprising a first segment called Box A and a second segment call, Box B, the first segment Box A comprising about 25 consecutive nucleotides and the second segment Box B comprising about six to eight consecutive nucleotides, a terminal segment 3 of nucleotides of the first segment Box A hybridizing with the second segment Box B, which causes by hybridization the formation of a first double-stranded structure this first double-stranded structure thus comprising a bulge. |