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filingDate 2006-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0228d2a2c1df59396de6296d18b82ceb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8824aa42cf6252744fdab48949a842ec
publicationDate 2008-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TN-SN06356-A1
titleOfInvention Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics
abstract The invention relates to a compound of formula (I) where n can represent a value between 1 and 6; - (C) n- represents C1-6 alkylidene group, where substituted by between 1 and 4 substituents; R1 represents a hydrogen atom, or a C1-6 alkyl group; R2 represents a hydrogen atom, a C1-6 alkyl or C3-6 cycloalkyl group substituted substituted by between 1 and 4 substituents; and B represents NR3R4, R3 and R4 independently representing C1-6 alkyl group or a hydrogen atom, or together representing C1-6 alkylidene group, C2-8 alkenylidene group, C1-3 alkylidene-O-C1-3 alkylidene; C1-5 alkylidene-N (R5) -C1-3 alkylidene group R5 represents a hydrogen atom, or a C1-3 alkyl or C1-6 alkylcarbonyl group, said C1-3 alkyl and C1-6 alkylcarbonyl groups; Substitutable, or an aminocycle which is linked by a carbon to the group -NR1- (C) n-, such as aziridine, azetidine, pyrrolidine, piperidine or morpholine, the groups R3, R4, the aminocycle, and the nitrogen atom being optionally substituted. The invention can be applied to therapeutics.
priorityDate 2004-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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