http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TN-2019000303-A1

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-08
filingDate 2018-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0221fb10856856dbca1a76f520957f64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16c0c375e673bd6549662fd609077e32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_710b39e8f281c6824e7809bcdeabb620
publicationDate 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TN-2019000303-A1
titleOfInvention Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation
abstract The present disclosure relates to compounds of formula (1): wherein RCG1 represents a reactive chemical group being reactive towards a chemical group present on a polypeptide such as an antibody; P represents H, OH or an activated O; and L represents a specific linker. The disclosure also relates to cryptophycin payloads, as well as to cryptophycin conjugates, to compositions containing them and to their therapeutic use, especially as anticancer agents. The disclosure also relates to the process for preparing these conjugates.
priorityDate 2017-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6438401

Total number of triples: 27.