| abstract |
FGF receptor-activating N-acyl octasaccharides of formula (I): wherein; R 1 represents an O-alkyl group optionally substituted by one or more aryl or cycloalkyl groups, R 2 represents a group OSO 3 - or hydroxyl, R 3 represents an alkyl, cycloalkyl or alkyl-cycloalkyl group, and R 4 represents a disaccharide of formula (II), R6 represents a disaccharide of formula (III) and R8 represents a disaccharide of formula (IV), where R5, R7 and R9 represent OSO3 or hydroxyl groups: Their preparation and their therapeutic application. |