http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-867314-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65846 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-665 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6584 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-26 |
| filingDate | 1979-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1981-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6383ca6b88ef1d6af009302f2abd28de |
| publicationDate | 1981-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-867314-A3 |
| titleOfInvention | Method of preparing optically active oxazphosphorin derivatives |
| abstract | Novel method optically active oxazaphosphorin derivatives represented by the general formula (I), <IMAGE> (I) wherein R1, R2 and R3 are respectively different from each other and are hydrogen atom(s), lower alkyl group(s), aralkyl group(s), or aryl group(s); and X is a halogen atom. The novel oxazaphosphorin derivative is prepared by reacting an optically active amino alcohol derivative represented by the general formula (II), <IMAGE> (II) wherein R1, R2 and R3 are the same as defined above, with a phosphorus compound represented by the general formula (III), POX3 wherein X is the same as defined above. The novel optically active oxazaphosphorin derivatives are useful as intermediates for preparing optically active cyclophosphamide derivatives which are useful therapeutical agents for curing against follicular lymphoadenopathy, lymphosarcomatosis, Hodgkin's disease, lymphosarcoma cell leukaemia, reticulum-cell sarcoma or the like. |
| priorityDate | 1978-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.