http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-856386-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df4e72183c5ee38a234212562dca6570 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D339-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D339-00 |
| filingDate | 1978-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1981-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ddcba263d9e2331eeae6aaf590bedc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1d4fb68e21e75b085cc3b9f36bc98e9 |
| publicationDate | 1981-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-856386-A3 |
| titleOfInvention | Method of preparing derivatives of 1,4-dithiepino-/2,3-c/-pyrrol or their salts |
| abstract | Dithiepino-pyrrole derivs. of formula (I) and their acids addn. salts are new: (A=phenyl, 2-pyridyl, 2-quinolyl, or 1,8-naphthyridin-2-yl; all opt. substd. by a halo, 1-4C alkyl or alkoxy, CN or NO2. R=H, 1-4C alkl or alkanoyl, or 2-4C alkenyl) They are prepd. e.g. by reacting a 4-(chlorocarbonyl)-1-R-piperazine with the corresp. 6-hydroxy dithiepino-pyrrole. (I) are useful as tranquillisers, anti-convulsants, hypnotics and muscle relaxants, generally given at 10-500 mg/day (oral adult dose). Their LD50 (orally in mice) is generally >0.9g/kg. A typical cpd. is 6-(4-methylpiperazino)carbonyloxy-7-(4-nitrophenyl).8-Oxo-3,4,7,8- -tetrahydro-2H, 6H-dithiepino (1,4) (2,3-c) pyrrole. |
| priorityDate | 1976-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.