http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-841586-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-452 |
| filingDate | 1978-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1981-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_376269f9e9cf75ece9a2cf46047a24c2 |
| publicationDate | 1981-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-841586-A3 |
| titleOfInvention | Method of preparing trans-4a-phenyl(substituted phenyl)-2,3,4,4a,6,7,7a-octahydro-1h-2-pyridines or their salts |
| abstract | Trans-4a-phenyl and substituted phenyl 2,3,4,4a,5,6 7,7a-octahydro-1H-2-pyrindines of the formula <CHEM> wherein: R1 is hydrogen, C1-C8 alkyl, CH2R3, <CHEM> in which: R3 is C2-C7 alkenyl, C3-C6 cycloalkyl, furyl, or tetrahydrofuryl; R4 and R5 independently are hydrogen, C1-C3 alkyl, or halogen; n is 0, 1, 2, or 3; m is 0 or 1, except that when m is o, n is other than O; X is CO, CHOH, CH=CH, S, or O, except that when n is O, X is other than S or O; R2 is hydrogen, hydroxy, C1-C3 alkoxy, or C1-C3 alkanoyloxy; and the non-toxic pharmaceutically acceptable acid addition salts thereof, are useful as analgesic agents having mixed agonist and antagonist properties. The compounds can be prepared by reacting a 4a-aryl-2-substituted-3,4,4a, 5,6,7-hexahydro-2-pyrindine with hydrogen and platinum oxide. |
| priorityDate | 1977-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.