http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-799670-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8cbc6261d883f27c8339ffb4b4cfeaa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-007 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
| filingDate | 1976-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1981-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d60161916e6444617ce890d9ee54a05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_340e47f36792b3f5c100bf5363cee75c |
| publicationDate | 1981-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-799670-A3 |
| titleOfInvention | Method of preparing derivatives of fusidic acid or its salts |
| abstract | A new series of fusidic acid derivatives, salts and easily hydrolyzable esters thereof, and processes for the preparation of these compounds are provided herein. The new compounds have the general formula in which the C24-25 bond is a single or a double bond, and in which Q1 and Q2 stand for or oxygen; A stands for oxygen, sulphur or a sulfinyl radical; R1 stands for a straight or branched alkyl radical having from 1 to 8 carbon atoms, or such straight or branched alkyl radical having from 1 to 8 carbon atoms when substituted by halogen atoms of hydroxy, alkyloxy, aralkyloxy, aryloxy, alkanoyloxy, aralkanoyloxy, aroyloxy, sulfhydryl, alkylthio, aralkylthio, arylthio, alkanoylthio, aroylthio, azido, nitro, cyano, thiocyano, hydroxycarbonyl, alkyloxycarbonyl, amino, alkylamino, dialkylamino, arylamino, ??anoylamino or aroylamino groups; an alkenyl or alkynyl radical having from 7 to 6 carbon atoms, a cycloalkyl radical having from 3 to 7 carbon atoms in the alicyclic ring, an aryl, aralkyl or heterocyclylalkyl radical, or such alkenyl or alkynyl radical having from 2 to 6 carbon atoms, such cycloalkyl radical having from 3 to 7 carbon atoms in the alicyclic ring, such aryl, such aralkyl or such heterocyclylalkyl radical when substituted by halogen, nitro, lower alkyl, hydroxy or alkoxy radicals: or a heterocyclic radical having 5 or 6 ring atoms, containing oxygen, sulphur or nitrogen atoms, and selected from 2- or 3-pyrrolyl, 2- or 3-furyl, 2- or 3-furfuryl, 2- or 3-thienyl, 2-, 3- or 4-pyridyl, 2-, 4or 5-pyrimidinyl, 2- or 3-pyrazolyl, imidazolyl, 1-methyl-2-immdazolyl, triazolyl, 5-methyl-1,2,4-triazol-3-y1, tetrazoyl, 1-methyl-1H-tetrazol-5-yl, thiazolyl, thiadiazolyl and 5-methyl-1,3,4-thiadiazol-2-yl: and pharmaceutically acceptable salts and easily hydrolyzable esters thereof. These compounds show interesting antimicrobial and pharmotokinetic properties. These compounds can be used in the treatment of bacterial infections in humans and animals. |
| priorityDate | 1975-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 148.