http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-784774-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d669af06cb2abbcd6823699582a97002 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-382 |
| filingDate | 1978-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1980-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12e86905858496340ce1dd157b5b9513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c03c128c9254fa92b72850dac4a00ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec8eb16d818a4f12c80663c451c9addf |
| publicationDate | 1980-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-784774-A3 |
| titleOfInvention | Method of preparing /3,3-di(thienyl-3)-3-oxypropyl/-(1-phenyl-1-oxypropyl-2)-amine or /3,3-di(thienyl-3)propen-2-yl/-(1-phenyl-1-oxypropyl-2-)-amine or their salts |
| abstract | [1,1-dithien-(3)-yl-1-hydroxy-(3)-propyl]-[1-phenyl-1-hydroxy-(2)-prop yl]-amine is prepared by condensing thien-(3)-yl lithium with a beta -halogen propionic acid alkyl ester of the formula <IMAGE> (II) where R is a lower alkyl group and Hal is chlorine, bromine or iodine, in an inert medium at a temperature below -50 DEG C. to form a compound of the formula <IMAGE> (III) which is then reacted with 2-amino-1-hydroxy-1-phenylpropane in an inert medium in the presence of a basic compound. The product cn be converted to [1,1-dithien-(3)-yl-(1)-propen-(3)-yl]-[1-phenyl-(2)-propyl]-amine by dehydration. |
| priorityDate | 1977-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.