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filingDate 1989-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1996-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1996-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber SU-1834290-A1
titleOfInvention METHOD OF OBTAINING FOOD PEPSIN
abstract The invention relates to methods for producing food pepsin and can be used in the production of milk-clotting enzymes for the dairy industry and medicine. The purpose of the invention is to improve the quality of the drug and increase its output. The method consists in carrying out acid hydrolysis of crushed mucous membranes of bovine sychugs with hydrochloric acid at pH 3.1–4.0 and temperature 40–45 ° C for 25–60 minutes, extraction in two stages, the first of which is carried out with acetate buffer at pH 5 , 0-5.5 in the presence of sodium benzoate at a concentration of 0.5-2.0%, and the second with the same buffer or ultrafiltrate obtained by concentrating the extract, followed by separating the phases of the extract by filtration and concentrating its liquid portion by ultrafiltration. Moreover, the total ratio of the acid solution and the extracting liquid to the raw materials is set at a rate of 5–10: 1. The method allows to improve the quality of the target product by reducing the amount of insoluble precipitate to 0.5–1.0% in the finished preparation and to increase the yield by 12–33 % compared with the known method. 1 tab.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2727431-C1
priorityDate 1989-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 41.