http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1710577-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fd215c6f04dc67eac2e8c0a4ca216d8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate | 1990-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1992-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0ba28bed75992090d4688a5e6133507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfef915c269c312b1928d1769bf96027 |
| publicationDate | 1992-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1710577-A1 |
| titleOfInvention | Strain of hybridous cultured mammalian cells mus musculus l - a producer of monoclonal antibodies to the human insulin |
| abstract | This invention relates to biotechnology and relates to the production of monoclonal antibodies to human insulin using a new hybridoma strain. The purpose of the invention is the preparation of a hybridoma strain producing monoclonal antibodies to a new determinant on a human insulin molecule. Strain D4B3 is obtained by hybridization of immune cells of BALB / c mouse lymph nodes with myeloma cells P3-X63-Ad8.653. Strain D4B8 is stored in the Specialized Collection of Transplanted Vertebrate Somatic Cells of the Institute of Cytology, USSR Academy of Sciences under the number VSKK (P) 440 D. The cells of strain D4B8 grow on RPMJ 1640 or DMEM medium with 10% fetal calf serum. The concentration of antibodies produced by the D4B8 strain is 50 µg / ml in the culture fluid, 20 mg / ml in ascites fluid. The antigenic determinant for antibodies D4B8 includes the A4 residue of the A chain and is conformational. ^ Fcrf ^ |
| priorityDate | 1990-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.