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filingDate 1983-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1991-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1991-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber SU-1694644-A1
titleOfInvention Process for preparing 9-hyoroxyandrost-4-end-3,17-dione
abstract The invention relates to the microbiological industry, and can be used in the manufacture of steroid pharmaceuticals. The purpose of the invention is the acceleration of the method. For carrying out the method, the strain Mycobacterlum fortultum ZIMET 10849 is used. Fermentation is carried out in the presence of a finely dispersed polymer of polyamide B, polyamide 11 or cyclohexanone-formaldehyde condensation resin at a concentration of 10 g / l of medium. At the same time, both the transformed sterol and the polymer can be introduced into the culture medium at different stages of fermentation both together and separately, and the transformation process is carried out either in a nutrient medium or in phosphate buffer. To obtain the desired product, both one of the sterols and their mixture are used. In all cases, an increase in the yield of the target product was obtained compared to transformation methods in the absence of a polymer. 2 hp f-ly, 1 tab.
priorityDate 1983-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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