| abstract |
The invention relates to heterocyclic compounds, in particular to the 3- [2- (2-oxo-1-pyrrolidinyl) ethylthio] -1,2,4-triazino [5,6-b] indole, which protects the liver from CCl poisoning. The goal is to identify compounds with a higher ability to protect the liver. Preparation of lead from 3-mercapto-1,2,4-triazino [5,6-b] indole in NaOH and N-2-chloroethylpyrrolidone-2 at 70 ° C for 5 hours. Yield 92.9%, mp. 221С, gross f la of CHNOS. LD3200 mg / kg. 1 tab. |