http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1616911-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ffb48902cf045bb30d646769fb5b56e6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 |
| filingDate | 1989-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1990-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac741f1030ba0e6c4abe2a96537b9ee3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd55060aac423781d1bde0aed2181da7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_690693bf6be3ed359a9fcf16e480d153 |
| publicationDate | 1990-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1616911-A1 |
| titleOfInvention | Method of producing 5(6)-10dobenzimidazols |
| abstract | The invention relates to heterocyclic substances, in particular the preparation of 5 (6) - iodobenzimidazole total f: CH = CJ-CH = CH-C = CN = CR-NH, where R = H, C 1-4 -alkyl, benzyl, hydroxyalkyl , halogenoalkyl, NH 2 , OH, SH, C (O) OH, S (O) 2 OH, with biological activity. The goal is to increase yield and expand the range of target substances while simplifying the process. The latter is obtained from R-substituted benzimidazole, which is acted upon by bromine and KJ or NAJ, followed by heating the mixture at 60-80 ° C until it becomes colorless and neutralized with base - NH 3 or NA 2 CO 3 . These conditions reduce the number of stages from 4 to 1 and increase the yield of the target substances from 10 to 80-84%. 1 tab. |
| priorityDate | 1989-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.