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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
filingDate 1987-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1990-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f07b1970862669a8d0a0b5a2f065adc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4f123c312fc76412fd9e04c58f10259
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publicationDate 1990-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber SU-1534396-A1
titleOfInvention Method of differential diagnosis of bacterial and virus meningitus
abstract The invention relates to medicine, in particular to medical microbiology, and can be used in the diagnosis of meningitis. The aim of the invention is to increase the sensitivity and simplify the method, as well as reduce the study time. For this, a 2% solution of agar on a 0.1 M biphthalate buffer or a 0.5% hypotonic solution of NACL with PH 6.2, a solution of polymyxin M sulfate in a concentration of 2-4 thousand U / ml, dry the mass of M. LYSODEIRTICUS test culture at a rate of 0.15% to the total volume of the medium, which is triturated in a mortar with 1-2 drops of buffer or hypotonic solution. An equal volume of polymyxin solution is added to the molten agar, the mixture is cooled to 44-55 ° C, after which the micrococcal culture is added and 4 ml are applied to slides. In a frozen medium, wells with a diameter of 2 mm are made at a distance of 1 cm from each other. The wells are filled with samples of cerebrospinal fluid, after which the slides are kept in a thermostat for 15-120 minutes. The presence of lysozyme is judged by the appearance of a lysis zone around the well during the specified observation period. If lysis is detected within 15-120 minutes, the bacterial etiology of meningitis is diagnosed, and in the absence of lysis,
priorityDate 1987-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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