http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1499901-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9859087545365e2993ad10386e0ce4d7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 |
| filingDate | 1987-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1991-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c5eb5b1543227fcfb2127c8f103a99c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e73a0e419e5feef6cc8a1049bc0faea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f25663e3cf8a448b20c53634899dcac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65b70d2ecd41627eaf6195d0dfb4f096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af190defddc1adf007f3644734e0529d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d17a9e3e4926db2a545fc57138b3253d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80eee8571e653aef219ad21788f56419 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_436c2ca8e6df9695a84b8e3ec4a6e25a |
| publicationDate | 1991-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1499901-A1 |
| titleOfInvention | N-quinoline-6-ylamide of pentaacetylglycyrrisinic acid displaying antiinelammatory activity |
| abstract | The invention relates to derivatives of glycyrrhizic acid, in particular to (3p, 20 () - P, c6-dioxo-30- (quinolin-6-lamino) -18A-olean-12-en-3-yl -2 -P - (, 3,4-tri-0-acetylglucopyranuronosyl) -6t-D-3,4-di-0-acetylglucopyranuronoid, an anti-inflammatory and anti-ulcer activity, the goal is to create a new, more active compound of the indicated class. by the reaction of trichloride anhydride pentaacetin glycyrrhenic acid with 2-amino quinoline in a solution of dry dioxane at 100 ° C "Yield 70%, t, b1. 201-204 C, gross formula Cg, Tests show that, at a dose of 100 mg / kg, the anti-inflammatory effect is similar to that of voltaren at a dose of 8 mg / kg, and exceeds the effect of glycyrrhizic acid and niglisin and doses of 100 mg / kg. The anti-spinal activity at a dose of 100 mg / kg exceeds activity of vitamin U at a dose of 1000 mg / kg, H table. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005053711-A1 |
| priorityDate | 1987-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.