http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1498387-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 1987-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29b5c11dcc2d2a6fb21b6a2dd4f16425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81a1c67f971142d0028ba02576d03563 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60a976796daadbbe1bf2acfb33b09ea6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5deae573f96f752b0d92fbc4f69792ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fba79d6b028bb98cefe8d656e83e8ede |
| publicationDate | 1989-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1498387-A3 |
| titleOfInvention | Method of producing derivatives of 1,2,5,6-tetrahydropyridine-3-carboxal-dehydroxym or their hydrochlorides |
| abstract | The invention relates to heterocyclic compounds, in particular, to the preparation of 1,2,5,6-tetrahydropyridine-3-carboxaldehyde oxime derivatives of the formula 1 NOR 2 = CH-C = CH-CH 2 -CH 2 -N (R 1 ) -CH 2 where R 1 is H or methyl, R 2 is linear or branched saturated C 1-3 = alkyl, linear or branched unsaturated C 2-4 alkyl, acetyl or dimethylaminoethyl, or their hydrochlorides having cholinomimetic activity. The purpose of the invention is the discovery of new, more active compounds of the indicated class. Obtaining the desired products are from the hydrochloride of the formula CHO-C = CH-CH 2 -CH 2 -N (R 1 - CH 2 ), where R is as indicated above, and the hydrochloride of the formula NH 2 OR 2 A, where R A is H, linear or branched saturated C 1-3 -alkyl, linear or branched unsaturated C 2 -C 4 - alkyl. The resulting compound of formula 1a NOR 2 A = CH-CH-CH 2 -CH 2 -N (R 1 ) -CH 2 , where R 1 and R A - are as indicated above, is isolated in free form or as hydrochloride, and in the case when R A is H, the compound of formula 1a is reacted with compound R B HAL, where R B is acetyl or dimethylaminoethyl, HAL is halogen. The resulting compound of the formula NOR B = CH-C = CH-CH 2 -CH 2 -N (R 1 ) -CH 2 where R 1 and R B are as indicated above, is isolated in free form or as hydrochloride. 5 tab. |
| priorityDate | 1986-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.