http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1490121-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b066c91d45fe3c5cb19fb02b7c9da16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1987-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b66ed8946f7e9ba0e6a48cdd2fca9545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a52d0fc5c91907003a8fd823d595210c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96e70802193a87dd543985384782d9b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05e14831ad9109b0f1be5d41d4d169bf |
| publicationDate | 1989-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1490121-A1 |
| titleOfInvention | Method of producing 5-hydroxy-5-methyl-4-oxo-3-arylpyrilidino /1,2-b/ pyrazols |
| abstract | The invention relates to heterocyclic substances, in particular the preparation of 5-hydroxy-5-methyl-4-oxo-3-phenylpyrrolidino [1,2-B] pyrazole, or 5-hydroxy-5-methyl-4-oxo-3- [4- bromophenyl] pyrrolidino [1,2-B] pyrazole, or 5-hydroxy-5,6-dimethyl-4-oxo-3-phenylpyrrolidino [1,2-B] pyrazole — intermediates for the synthesis of vitasomnin group alkaloids. The goal is to increase the yield of target products of the extended range and simplify the process. It is carried out by reacting the corresponding 3- [2-methyl-2,3-epoxypropionyl] -4-aryl-2-pyrazoline with N-bromosuccinimide, followed by treatment with triethylamine. These conditions allow to reduce the staging of the process from 4 to 2 and to increase the yield of the target substances by 30-35%. |
| priorityDate | 1987-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.