http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1446157-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d15d75caf8de38b057baab28f3d8210 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate | 1987-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78708f245953bc6cb752ab9d1180ceab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cb8b433f6928dfa727abba034873855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18698661d12f781113c9a0769b6a7a1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62c15530a6104bffe08c1dedc027b7d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61dbfb0448ea226f11662e5b9de7e8ca |
| publicationDate | 1988-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1446157-A1 |
| titleOfInvention | Strain of hybrid cultivated cells of mus musculus for producing monoclonal antibodies to membrane protein of escherichia coli |
| abstract | The invention relates to biotechnology and can be used to purify recombinant human interleukin-2. The aim of the invention is to obtain hybrid cultured cells of animal MUS musculus, producing monoclonal antibodies (MK) to membrane protein E. so11 4 kV, containing in the preparation of a portion of purified human recombinant interleukin-2 (P1-III-2). The strain is obtained by gabrdizatsii splenocytes of Balb / c mice immunized with RIL-2 human with HbZ-Ag8-653 myeloma cells. The secretion of ICA for 2-3 days of cultivation is 35-40 µg / ml of culture medium and 10-15 mg / ml of ascitic fluid. MAbs belong to the IgGi class. They specifically interact with E. coli membrane protein. 4kV The content of the E. coli impurity protein after purification of RIL-2 on a sorbent containing the obtained mAbs is 15%. 1 tab. F |
| priorityDate | 1987-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.