http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1441931-A1
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 |
filingDate | 1986-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | SU-1441931-A1 |
titleOfInvention | METHOD FOR DETERMINING BLASTOMOGENIC ACTIVITY OF CHEMICAL SUBSTANCES |
abstract | The method for determining the blastomogenic activity of chemicals by priming animals with a test substance, followed by slaughtering animals and determining changes in enzyme activity in the liver, characterized in that, in order to simplify the method by shortening the priming times of animals, the test substance is administered at a dose corresponding during the week daily, determine the activity of catalase, glutathione peroxidase, the content of reduced glutathione and conjugated dienes in the liver and at the same time A decrease in catalase and glutathione peroxidase activity by more than 50% compared with control, an increase in glutathione content by more than 50% and conjugated dienes by more than 100% determine the blastomogenic activity of the chemical during chronic intoxication. |
priorityDate | 1986-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 550.