http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1436872-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 |
| filingDate | 1985-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_791869f62ac82f2c50cef0e89d07d425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb453a5b84df81f5f81b2d897200e3ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ce30a7bbc123e6135d25a8075d76f97 |
| publicationDate | 1988-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1436872-A3 |
| titleOfInvention | Method of producing derivatives of pyrimidine |
| abstract | New pyrimidine derivatives of the formula:n wherein Z is a group selected fromn in which R 1 and R 2 are each hydrogen, alkenyl, ar (lower) alkyl or lower alkyl optionally substituted with epoxy, hydroxy, amino and/or lower alkylamino and R 5 is lower alkyl,n R' is hydrogen, aryl optionally substituted with lower alkyl, lower alkoxy a nd/o r halogen, or pyridyl optionally substituted with lower alkyl, R 4 is hydrogen, lower alkyl or phenyl optionally substituted with lower alkoxy, and Y is =0, =S or =N-R 6 , in which R 6 is lower alkyl; cyclo(lower)alkyl; ar(lower)alkyl optionally substituted with lower alkoxy; N-containing unsaturated heterocyclic group optionally substituted with lower alkyl; or aryl optionally substituted with hydroxy, lower alkyl, halogen or lower alkoxy, in which lower alkoxy substituent may be substituted with epoxy, hydroxy, amino and/or lower alkylamino, provided that Y is =N-R 6 when R 5 and R 4 are each hydrogen, and Y is =S or =N-R 6 when R' and R 2 are each hy d - rogen or lower alkyl and R 5 is phenyl, and pharmaceutically acceptable salts thereof, and processes for preparation thereof nad pharmaceutical composition comprising the same. n These derivatives and salts thereof are useful as cardiotonic, antihypertensive agent, cerebrovascularvasodilator and anti-platelet agent. |
| priorityDate | 1983-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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