http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1366517-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73368e8209d0ad5670a97a9c926d7edd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
| filingDate | 1986-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_449493dd352f4a652f3be2714d0f3ceb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3c4022ac8306ba10b929bf2d0481d5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e2c7c5d91ccc729c37d5658ae799c54 |
| publicationDate | 1988-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1366517-A1 |
| titleOfInvention | Method of obtaining 3-(beta-d-glucopyranosyl)-4-oxyhexahydropyrimidine-2-thion |
| abstract | The invention relates to substituted heterocyclic substances, in particular the preparation of 3 - (- D-glucopyrano-S1) -4-hydroxyhexahyropyrimidine-2-thione, an intermediate for the synthesis of effective inhibitors of cytidivine zaminase. To increase the yield of the target product and simplify the process in the reaction of the amine derivative (AM) and isothiocyanate (TC) and further cyclization, another AM, α-D-glucopyranosylamine and another TC, 3-isothiocyanatopropanal, temperature 0-5 ° C pyridine as a reaction medium. The method provides a yield of the target product up to 80% when using the starting materials without special protection of the hydroxyl and carboxyl groups. (L |
| priorityDate | 1986-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 168.