http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1340590-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-431 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-887 |
| filingDate | 1984-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1987-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c384ed2f160f3a45a9b663629c93cbc |
| publicationDate | 1987-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1340590-A3 |
| titleOfInvention | Method of producing 2-azacycloalkylthiopenem derivatives as salts with alkali metals |
| abstract | The invention relates to heterocyclic compounds, in particular, antibiotics of the 2-azacycloalkylthiopenem (AP) series of the formula H C- (H) C (-OH) CH-C () -SC-SR, 11 II I -N c-c (o ) it is in the form of their salts with alkali metals, where R, is the group XB-TSR -lCH-i -CH (CH2) group-CH2-C (OHHH-C (0) -tH--, 1;; 2; ; S; CHj; B - CHj; B - H; C (0) H, which as antibacterial agents can be used in medicine. For the detection of antibiotics of this series with lower values of minimum inhibitory concentrations, an AP analysis method was developed Obtaining AP lead from acc. of an ester (preferably p-nitrobenzyl) by catalytic (Pd) hydrogenolysis in tetrahydrofuran and water at room temperature, followed by treatment with an aqueous base solution () and isolation of the alkaline salt of AP. AP tests show that they have antibacterial activity at lower concentrations, than 2-ethyltyopenem. In addition, AP is more stable in the aquatic environment than 2-ethylthiopenem. 3 tab. CO from 4 About |
| priorityDate | 1983-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.