http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1340087-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_851cd6ac30becf8169f7f30fb7015fcc |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 1985-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1995-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a81007d75dfdebec35024f27729b4df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65cc4f326203bbb0ec53c733e90a5f18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e3c84260fbf51dc20dd04f0ec102f0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f5ade3a572ee809dd97ad622b404e42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae31b7c5e64080c1af50f2d569bbc088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_079d0222acd0a058c462fc6b581af48f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_721f649d9b3ddf4c0ea5b4044c36f84c |
| publicationDate | 1995-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1340087-A1 |
| titleOfInvention | YTTERBIUM COMPLEXES OF PORFIRINS AS LUMINESCENT SUBSTANCES FOR DIAGNOSIS OF MALIGNANT TUMORS |
| abstract | The invention relates to organometallic complexes, in particular, the ytterbium complexes of porphyrins (CP), which can be used as luminescent substances for the diagnosis of malignant tumors. The purpose of the invention is the creation of substances of the specified class, with better contrast. New CPs are obtained from porphyrin in a solution of 1, 2, 4 - trichlorobenzene and ytterbium acetylacetonate by boiling in a stream of nitrogen (2 h). Isolation is carried out by passing a cooled KP solution through an AlO layer, trichlorobenzene is washed with hexane, porphyrin is eluted with toluene, and then with acetone and then with a hot isopropanol-acetic acid solution (99: 1). The resulting raspberry solution is poured into water and the CP is extracted with chloroform, which does not contain traces of HCl. Yield 34.7%, m.p. > 300 ° C. KP tests show that they allow you to record the peak of luminescence in the region of 975 nm or the entire spectrum in the region of 900 - 1050 nm of diagnosed organs or tissues. KP toxicity at porphyrin level. 1 tab. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2697418-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2766513-C1 |
| priorityDate | 1985-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.