| abstract |
PCT No. PCT/HU84/00004 Sec. 371 Date Sep. 20, 1984 Sec. 102(e) Date Sep. 20, 1984 PCT Filed Jan. 20, 1984 PCT Pub. No. WO84/02906 PCT Pub. Date Aug. 2, 1984.Compounds are disclosed of the formula (I) <IMAGE> wherein A1 is a valence bond or a C1 to C5 straight or branched chain alkylene group unsubstituted or substituted by hydroxy or aminocarbonyl; B is a valence bond or a double bond; R3 is hydrogen or C1 to C4 alkyl; R2 is a phenyl or phenoxy group unsubstituted or substituted by one or two C1 to C4 alkyl groups, C1 to C4 alkoxy groups, or halo substituents; or R2 is an amino group, a diphenylmethyl group, or an R4 -NH-CO- group in which R4 is 2,6-dimethyl-phenyl; or a pharmaceutically acceptable acid addition salt thereof. The compounds possess anti-arrhythmic activity and exert little or no hypotensive side effects. |