http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SU-1218812-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f70af90a21bd6491d704dfda9c45ed02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 |
| filingDate | 1983-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1992-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_248a081ce8e1182b94a19fa359c80043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbd96bcda09f1f6e78dad1b3cc0617e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72b39cf27e59bea5d692dba2f5c0e34e |
| publicationDate | 1992-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | SU-1218812-A1 |
| titleOfInvention | Method of simulating teratogen effect |
| abstract | ) 7 embryos out of 30 survivors died and developmental abnormalities occurred. In parallel with 5 rats, 13 mg of KGV1 ml of 25% ethanol was administered intraperitoneally. At the same time and the next day, 0.4 ml of tween and 0.6 ml of saline were administered intragastrically with a probe. An autopsy of females on the 20th day showed that one embryo out of 60 survivors had developed abnormalities at the time of the autopsy (absence of one finger on the forelimbs),. The optimal doses of injected drugs are 500 mg / kg of thalidomide and 65 mg / kg of QOL, at which the frequency of malformations is 71%, and in 13 out of 99 (13%) fruits, the leading anomalies of ta- were observed. .LydoMyDnogo syndrome - fockbels and amelia, along with anomalies of the eyes and ear. (Lu go |
| priorityDate | 1983-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.