| abstract |
Novel compounds of the general formula (I> <IMAGE> wherein R<1> stands for hydrogen or lower alkyl, R<2> is hydroxy and R<3> is hydrogen, or R<2> and R<3> form together a valence bond, Q represents a carbon or nitrogen atom, A is hydrogen, hydroxymethyl, lower alkyl, phenyl-lower alkyl or lower alkoxycarbonyl, n is 0 or 1, B stands for nitro, cyano, halogen, optionally halogeno- or nitro-substituted phenyl, pyridyl, quinolyl or a group of the general formula (IV), <IMAGE> in which R<5> is hydrogen or lower alkylcarbonyl and R<4> stands for nitro, amino, trifluoromethyl, lower alkyl or lower alkoxy, or A and B, together with the adjacent carbon atom to which they are attached, form a 5- or 6-membered, optionally substituted heterocyclic ring which contains not more than two identical or different nitrogen and/or oxygen and/or sulfur heteroatom(s) and optionally one or two exocyclic oxygen atom(s) and/or sulfur atom(s) and/or imino group(s), with the proviso that if Q represents a nitrogen atom, n is O and B stands for a group of the general formula (IV), and with the further proviso that if Q represents a carbon atom, B is other than a group of the general formula (IV), or a biologically acceptable acid addition salt of a compound of the general formula (I) with basic character, have antimicrobial activity and are of value as feed additives for use in animal husbandry. |