| abstract |
Compounds represented by the following general formula (1) or (2): (FORMULA) (wherein R<s1>s represents H, a lower alkyl, lower alkenyl or phenyl-lower alkyl, R<s2>s represents H or a lower alkyl, A represents a lower alkylene, R<s3>s represents a lower alkyl optionally having a hydroxy group a lower alkoxy-lower alkyl, lower alkanoyloxy-lower alkyl or benzoloxy-lower alkyl, R<s4>s represents a cycloalkyl optionally having a hydroxy group, cycloalkyl-lower alkyl, phenyl, phenyl-lower alkyl optionally having a lower alkoxy group on the phenyl ring, lower alkyl optionally having a hydroxy group, hetero ring group or hetero ring-substituted lower alkyl, and R<s3>s and R<s4>s may form, together with the adjacent N, a group represented by the formula of (FORMULA) (wherein R<s5>s represents phenyl, cycloalkyl or phenyl-lower alkyl, and B represents methine or N), provided that, when R<s3>s represents the lower alkyl, R4 represents the aforesaid group other than cycloalkyl, cycloalkylalkyl, and lower alkyl, and the bond between the 3- and 4-positions on the carbostyryl skeleton represents a single or double bond], the salts thereof, and process for preparing same. These compounds have the effects of preventing and curing thrombosis. |