abstract |
The method of obtaining cephalosporin derivatives of the general formula C C ONH-pY y Ke N CT l V R, O COORz-SNGSOS | O where RJ is a hydrogen atom or a protecting group forming an ester; R. a. Of hydrogen or a protective group forming an ester; R, a hydrogen atom or methyl; R ,, hydrogen or chlorine atom, methyl, vinyl, methoxy group, methoxymethyl, methylthiomethide or acetoxymethyl, and one of RI and R4 means a hydrogen atom or their salts with alkali metals, when R (and / or Rj is a hydrogen atom, in the form of syn -isomers, about tl and h aJtpsc and also with the fact that the compound of the general formula H, Nr-rV, COOE R and E.L have the indicated values of R. cha VIA, or its reactive derivative in the amino group, or its salt is subjected to interaction with compound of general formula |