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filingDate 1979-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1984-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_193e6786f0e3bcaeaf76d37c61b724fc
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publicationDate 1984-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber SU-1110386-A3
titleOfInvention Process for preparing 1-oxadethiacephalosporins
abstract METHOD OF OBTAINING 1-OXADATIAATSEPHALOSPORINS of the general formula RCONH-I -1J SNgX CQOW where R is free phenyl, phenyl substituted by nitro or cyano, methyl or chlorine atom, benzyl or phenoxymethyl; E is hydrogen or methoxy; SOOB - carboxy, benzyloxycarbonyl or diphenylmethoxycarbonyl; X is hydrogen or halogen or 1-methyltetrazol-5-ylthio group, characterized in that the compound of the general formula is as follows: where R, E, COOB, and X have the given values; Z - halogen, hydroxy-, trifluoroacetoxy-, phenylthio, Ci-Cit-alkylthio- or i-phenylselenyl-group, is treated with alkali methylate of CO metal, piperidine, 1.5C-diazabicyclo C4,3,01non-5-ene or 1,5-diazabicyclo C5,4,0 undec-5-ene, when Z is a halogen atom, or thionyl chloride or phosphorus oxychloride in the presence of pyridine or methylpyridine, or pivalo or isocyanate, when Z is oxy- or trifluoroacetoxy, or M-chloroperbenzoic 00 O ) acid or peracetic acid, when Z is phenylthio, alkylthioyl or phenylselenyl, in a solution with: temperature from -50 ° C. C to the boiling point of acetone under reflux for a period of time from 10 minutes to 5 days.
priorityDate 1977-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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