| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eccd894c99fea2d1c0c8735872bb2309 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-72 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
| filingDate |
1996-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13520e5ed790bf043e89cd945680a264
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_082cccc1084f5f1d5bc0663e603ba34c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b46dd9bdbe8f4873945b2a69a2830393
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40680298dfad2356bfa3c30416af6f08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba0e141fdee23b99196af1ac549d3d0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cc848d421b09a24471af9c254fb0f8d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e85c7e68c6933fc292ddfe1aad3b4fa4 |
| publicationDate |
1998-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
SK-74098-A3 |
| titleOfInvention |
Process for the preparation of recombinant proteins in e.coli by high cell density fermentation |
| abstract |
The invention relates to a fed-batch fermentation method with particular host-vector systems of E. coli for effective formation of recombinant proteins, in particular recombinant antibody molecules, preferably antibody fragments such as mini antibodies. In the conditions given the E. coli cells can grow at the maximum specific growth rate to very high cell densities. When recombinant product formation starts, only the product formed acts in a limiting manner on growth. Growth limitation by substrates or metabolic by-products does not occur. Consequently, large amounts of recombinant proteins can be produced in relation to space and time. |
| priorityDate |
1995-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |