| abstract |
Novel benzenesulfonamide derivatives represented by the following general formula (I) are provided: <CHEM> wherein R<1> represents hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxyl group, or nitro group; R<2> represents a C4-C8 alkyl group which is substituted with one or more fluorine atoms; R<3> represents hydrogen atom or a lower alkyl group; X represents sulfur atom or a group represented by CH=CH; and n represents an integer of from 2 to 4. Medicaments comprising said compound as an active ingredient can be used for preventive and/or therapeutic treatment of thrombosis, asthma, or allergic diseases. |