| abstract |
The production of the substance called tramadol of hydrogenchloride is based on that principle,that the fractions of the row tramadol salt with the different level of impurities content are cleaned based on the crystallisation with use of the organic solvent, represented by the alcohol C1 up to C6 or by the systems of solvents closed to the alcohol. The above mentioned principle can be applied in the pharmaceutical chemistry, when producing substances closed to the narcotic analgesic called tramadol of hydrogenchloride. |