abstract |
Prodn. of 5-formylamino-pyrimidines of formula (I) comprises reductive formylation of the corresp. 5-nitroso-pyrimidines (II) with formic acid in the presence of a formate salt and a noble metal catalyst: R1-R3 = H, OH, SH, NH2, 1-4C alkylamino, halogen, 1-4C alkoxy, 1-4C alkylthio, 1-4C alkyl or aryl. |